André Faure, ALLOX Co-founder and CDO, will present at the EMBO | EMBL AI and biology Symposium, on Wednesday, March 13th at 14:15. 

The talk will cover the development and applications of MoCHI: a flexible tool to fit mechanistic models to deep mutational scanning (DMS) data, which represents a core building block of the ALLOX computational platform. The software is freely available and described in a January 2024 preprint on BioRxiv.

The combination of DMS and MoCHI allows biophysical measurements to be performed at scale, including the construction of complete allosteric maps of proteins. A major goal of the company is to use these maps to develop allosteric modulators targeting proteins of high therapeutic value.

The aim of this symposium is to catalyse synergistic interactions between AI researchers in different subfields of biology by exploring shared theoretical approaches, cross-domain experiments, and data integration, as well as shared topics in dissemination of tools and collaboration with experimental labs.